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CBG: What Is It and What Are the Benefits?

CBG: What Is It and What Are the Benefits?

Updated July 22, 2026

CBG, or Cannabigerol, is a naturally occurring, non-psychoactive cannabinoid found in the hemp plant. Often called the "mother cannabinoid," it's the precursor compound from which CBD, THC, and other cannabinoids are synthesized during the plant's growth. Like CBD, CBG is hemp-derived, federally legal, and shouldn't produce any intoxicating effects.

You've probably heard plenty about CBD by now, but CBG is quietly emerging as the next significant cannabinoid in plant-based wellness. Think of it as CBD's more energizing cousin: same hemp source, same clear-headed experience, but with a distinct personality of its own.

CBG may not be a household name yet, but early research suggests it may help support everything from focus and mood to inflammation and everyday discomfort. And as more people discover what minor cannabinoids can do, CBG is earning a well-deserved spot in the conversation.

If you're curious about adding something new to your wellness routine, let's break down what CBG is, how it works in the body, and how to use it—plus a few Treadwell Farms products to help you get started.

CBG at a Glance

What is CBG?

Cannabigerol (CBG) is a non-psychoactive cannabinoid found in hemp.

Is CBG psychoactive?

No. Like CBD, CBG does not produce intoxicating effects.

How does CBG differ from CBD?

CBG binds directly to CB1 and CB2 receptors in the endocannabinoid system;

CBD interacts more indirectly. CBG tends to feel more energizing, while CBD is more calming.

What may CBG help with?

Early research suggests potential support for focus, mood, anxiety, inflammation, and discomfort—though CBG is not intended to treat or diagnose any condition.

Is CBG legal?

Yes. Hemp-derived CBG is federally legal under the 2018 Farm Bill when derived from hemp containing less than 0.3% THC by dry weight.

Where does Treadwell Farms' CBG come from?

Our CBG is sourced from US-grown hemp, extracted in small batches, and third-party tested for purity and potency.

What products contain CBG?

Treadwell Farms offers CBG in a topical (Rapid Relief Cream) and an ingestible Focus CBG Gummy—plus naturally-occurring CBG in all full-spectrum extracts and gummies.

What Is CBG (Cannabigerol)?

So, what is CBG exactly? Often called the "mother cannabinoid," CBG is a compound in the hemp plant that starts out as CBGa (cannabigerolic acid). CBGa is the precursor from which other cannabinoids, like CBD and THC, are synthesized during the plant’s growth. 

As the hemp plant matures, most CBGa is converted into other compounds (which is why CBGa is found in higher concentrations in young hemp plants). Through a process called decarboxylation that occurs when the plant is exposed to heat and light, the residual CBGa transforms into CBG.

CBG is considered a minor cannabinoid in CBD- and THC-dominant plants because it’s present in smaller amounts than the major cannabinoids those plants are bred for. But don’t let the term "minor" fool you! CBG actually plays a significant role in the hemp plant’s development and therapeutic potential.  

Furthermore, new advancements have resulted in CBG plant breeders developing new plants that genetically feature higher quantities of CBG. Through this advancement, Treadwell Farms is able to create CBG-focused products without harvesting the CBG from CBD and THC plants.

Importantly, CBG is non-psychoactive, meaning it won’t produce an intoxicating effect. Like CBD, it offers wellness support without altering your mental state, making it a safe and appealing option for everyday use.

CBG vs. CBD: Key Differences and Similarities

Let’s take a look at the comparison between CBG vs CBD. While CBG and CBD share some common features—both are non-psychoactive and federally legal—they interact with the body in distinct ways and offer different effects. Understanding their differences can help you make informed decisions about which cannabinoid (or combination) suits your wellness needs.

How CBG and CBD Work Differently

CBG binds directly to your body’s CB1 and CB2 receptors, which are part of the endocannabinoid system (ECS). Your ECS helps regulate functions like mood, appetite, pain response, and inflammation. This direct interaction may explain CBG’s effects, which tend to feel more targeted and energizing.

By contrast, CBD works indirectly, influencing the ECS without binding strongly to those receptors. This subtle mechanism contributes to CBD’s gentle and broad-spectrum support.

Despite their differences, both CBG and CBD are non-intoxicating and can be used daily to support wellness goals.

Effects Profile Comparison

CBG is often described as uplifting and energizing, which is why so many people reach for CBG for focus during the day. Some users compare its effects to a light boost, like enjoying a cup of coffee but without those unwanted jitters afterward. 

On the other hand, CBD is known for its calming and relaxing properties. Many people use CBD to have a better day and as part of a bedtime routine in the evening to promote restful sleep. For example, Treadwell Farms’ Evening Blend CBD Extract is a full-spectrum CBD tincture, with the naturally-occurring ratio of CBG, that is designed to support relaxation for a restorative slumber.

a woman sitting at a table doing computer work in a kitchen

CBG Benefits: What the Research Says

Research into CBG benefits is still in its early stages, but initial studies suggest a wide range of potential therapeutic effects. These benefits may complement or enhance those of CBD, especially when the two are used together.

Anti-Inflammatory and Pain Relief

One of the top CBG effects is its potential to reduce pain and inflammation, and it works differently than CBD. Because CBG binds with CB2 receptors (which are linked to immune response), it may help target localized pain and swelling more effectively.

This makes CBG especially appealing in topical products, like Treadwell Farms’ Rapid Relief Cream with CBG, which combines the soothing effects of CBG and CBD to support tired muscles and sore joints.

Scientific studies continue to explore CBG’s effects. A 2024 research review notes that CBG shows promise in relieving symptoms of inflammatory bowel conditions due to its anti-inflammatory properties.

Mood and Anxiety Support

A recent clinical trial showed that CBG usage resulted in a 26.5% reduction in anxiety symptoms, suggesting it may help you manage stress and mental tension without causing sedation.

CBG offers clear-headed stress relief, making it suitable for daytime use. Early evidence also points to CBG’s potential to support mood balance and help manage symptoms of depression.

Additional Therapeutic Properties

Beyond inflammation and mood, researchers are exploring CBG’s broader therapeutic potential for:

  • Neuroprotective benefits for degenerative conditions like Huntington’s disease.

  • Antibacterial effects, including activity against drug-resistant strains like MRSA.

  • Eye health support through reducing intraocular pressure, which may benefit those with glaucoma.

  • Appetite stimulation, potentially useful for people dealing with low appetite due to illness or medication.

Topical vs. Ingestible CBG: Rapid Relief Cream vs. Focus CBG Gummy

Because Treadwell Farms' full-spectrum products retain the hemp plant's complete cannabinoid profile, all of them naturally carry small amounts of CBG right alongside CBD. Two of our products, though, are formulated to put CBG front and center, and they go about it in very different ways.

Rapid Relief Cream is built for a single sore spot. You apply it right where it hurts, and (thanks to its advanced transdermal formula) it absorbs through your skin to deliver cannabinoids deep into the skin for targeted, localized support. Focus CBG Gummy takes the opposite approach: an ingestible CBG format for a whole-day, whole-body effect designed to support mental clarity and focus. It may also help ease physical tension, making it a good option if you like the idea of the cream but want something systemic too.


Format

Best For

THC Level

Onset 

Rapid Relief Cream

Topical

Targeted muscle and joint discomfort

Trace amount

Minutes, applied directly

Focus CBG Gummy

Ingestible

Whole-day mental clarity and focus

5mg per serving

30–90 minutes


Our Rapid Relief Cream with CBG + CBD delivers that targeted comfort by blending equal parts CBG extract with our full-spectrum CBD oil, along with hemp-derived terpenes and botanical ingredients like menthol, spearmint, aloe, and arnica. Simply rub a small amount into your skin wherever you're experiencing discomfort. If you'd like to see how a topical like this works beneath the surface, our guide to Transdermal CBG Cream breaks down the science, and you'll find more options for ongoing comfort in our Relief & Recovery collection.

Our Focus CBG Gummy is Treadwell Farms' highest-potency gummy yet: 15mg of CBG, 5mg of THC, and 5mg of CBD, flavored with natural mango, whose natural terpene profile shares beta-caryophyllene with hemp itself. Each cannabinoid in these CBG gummies plays its own role: CBD works broadly throughout the body, THC engages your brain and central nervous system directly, and CBG binds to those same receptors as both, though more directly than either one alone. 

This kind of layered mechanism is explored in a recent comprehensive review of CBG's molecular mechanisms and therapeutic potential, and researchers are also examining CBG's relevance beyond focus and comfort, including a possible role in supporting cardiovascular health, an area still under active study. It's a fitting daytime companion for anyone who already reaches for our Relief Gummies in the evening, and a natural complement to Rapid Relief Cream for those wanting a systemic option alongside a targeted one. Explore the full Focus & Energy collection to see how it fits alongside our other daytime picks.

Because this gummy contains 5mg of THC per serving, still below the federally legal 0.3% level but above the trace amount found in most Treadwell Farms products, it's intended for adults 21+ only and isn't the right choice for anyone concerned about drug testing. You can review the full COA test results before trying it. Unlike our general wellness gummies, Focus CBG Gummy is meant to be taken as needed. Start low and see how your body responds; our Safety and Considerations section below has more on that.

One sore knee calls for the cream. A foggy, low-focus afternoon calls for the gummy.

Safety and Considerations

Like CBD, CBG is generally well-tolerated. Most users report minimal side effects, which may include:

  • Dry mouth

  • Dizziness

  • Low blood pressure

Because research on CBG is still emerging, it’s wise to start with a low dose and see how your body responds. Always consult with your healthcare provider, especially if you are pregnant, breastfeeding, or taking prescription medications.

Although CBG shows exciting promise, long-term safety studies are limited. As with all plant-based supplements, ongoing research will help deepen our understanding of its full effects.

The Future of CBG in Wellness

As you become more aware of minor cannabinoids and their unique properties, CBG is likely to play a larger role in your natural wellness routine. There’s strong potential for combination products that blend CBG with CBD, terpenes, and other cannabinoids for more tailored support.

At Treadwell Farms, we’re committed to hemp education and quality and innovation in our cannabinoid-rich products. Whether you’re exploring CBG for the first time or looking to enhance your existing routine, we invite you to explore our selection and find the right plant-powered solution for your needs!

CBG Frequently Asked Questions

What does CBG feel like?

Most people describe CBG as clear-headed and mildly energizing rather than sedating. Unlike CBD, which many use for relaxation, CBG is often preferred for daytime use and focus support. It should not produce a "high" or intoxicating effect.

How much CBG should I take?

As with all cannabinoids, start with a low dose and increase gradually based on how your body responds. Follow the suggested serving size on the product label, and consult your healthcare provider if you have any questions, especially if you are taking prescription medications.

Can you take CBG and CBD together?

Yes. CBG and CBD are often used together and may work synergistically as part of the entourage effect. Full-spectrum CBD products from Treadwell Farms, including our CBG gummies, naturally contain small amounts of CBG alongside CBD and other hemp compounds.

Is CBG safe?

CBG is generally considered well-tolerated, and early research suggests a favorable safety profile. Mild side effects may include dry mouth or dizziness. Long-term safety research is still ongoing. Always consult your healthcare provider before adding any new supplement to your routine.

How is CBG different from CBD for focus?

When it comes to CBG vs CBD for focus, the CBG interacts directly with CB1 and CB2 receptors in the endocannabinoid system and is often associated with a more targeted, energizing effect compared to CBD's broader calming support. This makes CBG a popular choice among people looking for daytime mental clarity.

Does the Focus CBG Gummy contain THC?

Yes. The Focus CBG Gummy contains 5mg of THC per serving, still below the federally legal 0.3% by dry weight level but above the trace amount found in Treadwell Farms products that only contain our full-spectrum CBD (products not enhanced with additional cannabinoids). It's intended for adults 21+ only and isn't a good fit for anyone who may be subject to drug testing. You're welcome to review the full [COA test results] anytime, and if you're curious about other daytime options, our Focus & Energy collection has more to explore.

What is the best way to take CBG?

CBG is available in oils/tinctures, topicals, and gummies. For whole-body support, a full-spectrum gummy that naturally contains CBG is a good starting point, or if you're looking for a stronger, more concentrated daytime effect, our Focus CBG Gummy is built specifically around it. For targeted muscle and joint comfort, a CBG-rich topical like Treadwell Farms' Rapid Relief Cream may be a good fit.

About the Author 

Treadwell Farms | Jammie Treadwell

Jammie Treadwell has co-owned and operated Treadwell Farms since 2019 handling everything from nursery operations to product development. Treadwell and her parents continue her family's Florida farming legacy by intentionally creating natural, small-batch artisanal hemp products trusted and tested with the community in mind.

 

Sources

  1. Anderson, B. D., Sepulveda, D. E., Nachnani, R., Cortez-Resendiz, A., Coates, M. D., Beckett, A., Bisanz, J. E., Kellogg, J. J., & Raup-Konsavage, W. M. (2024). High Cannabigerol Hemp Extract Moderates Colitis and Modulates the Microbiome in an Inflammatory Bowel Disease Model. The Journal of pharmacology and experimental therapeutics, 390(3), 331–341. https://doi.org/10.1124/jpet.124.002204.

  2. Cuttler, C., Stueber, A., Cooper, Z. D., & Russo, E. (2024). Acute effects of cannabigerol on anxiety, stress, and mood: a double-blind, placebo-controlled, crossover, field trial. Scientific Reports, 14(1). https://doi.org/10.1038/s41598-024-66879-0

  3. Cannabinoids offer new hope for safe and effective pain relief. (2025, January 21). Yale News. https://news.yale.edu/2025/01/21/cannabinoids-offer-new-hope-safe-and-effective-pain-relief 

  4. Krzyżewska, A., Kloza, M., & Kozłowska, H. (2025). Comprehensive mini-review: therapeutic potential of cannabigerol – focus on the cardiovascular system. Frontiers in Pharmacology, 16. https://doi.org/10.3389/fphar.2025.1561385

  5. Li, S., Li, W., Malhi, N. K., Huang, J., et al. (2024). Cannabigerol (CBG): A Comprehensive Review of Its Molecular Mechanisms and Therapeutic Potential. Molecules, 29(22), 5471.  https://doi.org/10.3390/molecules29225471